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Rapamycin, an mTOR inhibitor, similarly promotes autophagy, attenuates pathological remodeling and is now in phase II clinical trials for HFpEF (Tables 1 and 2)
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Both groups reported significantly reduced patient capacity levels (Table 1), and ME/CFS patients had, on average, a lower percentage of their preillness capacity compared to long COVID patients (41.0 ± 18.5% vs 50.6 ± 20.4%)
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